NCT07330154 The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
| NCT ID | NCT07330154 |
| Status | Recruiting |
| Phase | — |
| Sponsor | King Abdullah University Hospital |
| Condition | Wound Healing |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2025-10-29 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2025-10-29 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are: * Does NBF gel enhance wound healing after graft harvesting from the palate? * Does NBF gel reduce the number of inflammatory mediators after surgery? * Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing. Study steps include: * Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks. * Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30). * Wound fluid samples will be collected on days (0, 1, 2, 4, 7). * Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.
Eligibility Criteria
Inclusion Criteria: 1. Patients with gingival recession that is indicated for root coverage or need for phenotype modification. 2. 18 years or older. 3. absence of systemic disease 4. Non-smoker 5. No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months Exclusion Criteria: 1. Pregnant or lactating woman. 2. patients with immune or systemic diseases. 3. Patients with an allergy to any ingredient in the gel.
Contact & Investigator
Lana Bader, DClinDent Perio
STUDY DIRECTOR
Jordan University of Science and Technology
Frequently Asked Questions
Who can join the NCT07330154 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Wound Healing. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07330154 currently recruiting?
Yes, NCT07330154 is actively recruiting participants. Contact the research team at lmbader4@just.edu.jo for enrollment information.
Where is the NCT07330154 trial being conducted?
This trial is being conducted at Irbid, Jordan.
Who is sponsoring the NCT07330154 clinical trial?
NCT07330154 is sponsored by King Abdullah University Hospital. The principal investigator is Lana Bader, DClinDent Perio at Jordan University of Science and Technology. The trial plans to enroll 36 participants.