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Recruiting NCT07496905

The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial

Trial Parameters

Condition Pain in Endometrial Biopsy
Sponsor Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex FEMALE
Min Age 18 Years
Max Age 55 Years
Start Date 2025-01-01
Completion 2026-12-01
Interventions
endometrial biopsyTenaculum ApplicationValsalva Maneuver

Brief Summary

Endometrial sampling with a pipelle is a common procedure used to collect a small sample from the lining of the uterus. During the procedure, the cervix is sometimes held with a surgical instrument called a tenaculum, which may cause pain and anxiety for some women. The Valsalva maneuver is a simple technique in which a person takes a deep breath and pushes as if trying to exhale forcefully. This increases pressure inside the abdomen and may help keep the uterus and cervix more stable during the procedure. This study aims to compare pipelle sampling performed with the Valsalva maneuver to the standard method using a tenaculum. The study will evaluate whether the Valsalva maneuver can reduce pain and anxiety while maintaining procedure success and improving patient satisfaction.

Eligibility Criteria

Inclusion Criteria: -Endometrial sampling indication in reproductive age group of patients over 18 years of age, who can communicate in Turkish. Exclusion Criteria: * Patients under 18 years of age - postmenopausal * Pregnancy * Patients with known stenotic cervical os * Patients with a history of acute cervicitis; * Patients with intense anxiety; * Need for simultaneous endocervical curettage; * Need for general or local anesthesia * Having used analgesic medication before the procedure; * History of a known malignancy, uterine anomaly, or leiomyoma affecting the cervical canal or uterine cavity, or uterine prolapse; * Patients with known chronic plevic pain

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