NCT07035314 The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain.
| NCT ID | NCT07035314 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ain Shams University |
| Condition | Tonsillitis Chronic |
| Study Type | INTERVENTIONAL |
| Enrollment | 75 participants |
| Start Date | 2025-03-08 |
| Primary Completion | 2025-07-01 |
Trial Parameters
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Brief Summary
The aim of this study is to compare the efficacy of adding paracetamol to systemic non-steroidal anti-inflammatory drugs (NSAIDs) versus adding dexamethasone as local infiltration to paracetamol on post tonsillectomy pain control.
Eligibility Criteria
Inclusion Criteria: * Age: Between 4-10 years. * Indications of tonsillectomy such as: * Recurrent acute attacks at least 7 episodes in the past year or at least 5 episodes per year for 2 years or at least 3 episodes per year for 3 years. * Chronic tonsillitis and hypertrophy of tonsils causing sleep apnea, difficulty in deglutition, interference in speech. * Tonsillectomy by cold dissection only. * American Society of Anesthesiologists (ASA) classification 1,2 (Normal Health, Mild systematic disease). Exclusion Criteria: * Patients with age less than 4 and more than 10 years. * Indications of tonsillectomy other than chronic tonsillitis such as lymphoma. * Patients on chronic steroid therapy * Hemoglobin level less than 10 gm/dL * Presence of acute infection in the upper respiratory tract, acute tonsillitis * American Society of Anesthesiologists (ASA) classification ASA 3,4 (Severe systematic disease such as uncontrolled Diabetes, cardiac disease, liver or kidney disease, life threat