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Recruiting NCT07489807

NCT07489807 The Effect of Mild-gain Amplification on Tinnitus Perception in Normal Hearing Adults

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Clinical Trial Summary
NCT ID NCT07489807
Status Recruiting
Phase
Sponsor Technical University of Denmark
Condition Tinnitus
Study Type INTERVENTIONAL
Enrollment 15 participants
Start Date 2025-04-01
Primary Completion 2026-08-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Hearing Aid with NR_4

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 15 participants in total. It began in 2025-04-01 with a primary completion date of 2026-08-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study investigated the effect of mild gain amplification (8dB covering 1 Hz to 8kHz) as tinnitus treatment for participants with normal hearing and compared these effects with an active placebo condition using hearing aids without amplification in a double-blinded crossover study. 12 participants with normal hearing and chronic tinnitus were included in the study. Two different hearing aid treatments were provided for 3 weeks each: mild gain amplification that provided 8dB gain in the frequency range from 1 Hz to 8 kHz and no amplification, acting as placebo. The effect of the two treatments on tinnitus distress was evaluated with the Tinnitus Functional Index (TFI) questionnaire. The effect of the treatment on tinnitus loudness and annoyance were evaluated with a visual analog scale (VAS).

Eligibility Criteria

Inclusion Criteria: * Daily bothersome tinnitus for at least 3 months (TFI\>15) * Normal hearing (25 dB HL from 125 Hz to 8 kHz) * Inexperienced hearing aid user Exclusion Criteria: * Meniere's disease, Tosclerosis, Stapedectomy, Stapedotomy and Tympanoplasty * Objective or pulsatile tinnitus * Hearing thresholds \>25 dB from 125 Hz to 8 kHz

Frequently Asked Questions

Who can join the NCT07489807 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Tinnitus. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07489807 currently recruiting?

Yes, NCT07489807 is actively recruiting participants. Visit ClinicalTrials.gov or contact Technical University of Denmark to inquire about joining.

Where is the NCT07489807 trial being conducted?

This trial is being conducted at Lyngby, Denmark.

Who is sponsoring the NCT07489807 clinical trial?

NCT07489807 is sponsored by Technical University of Denmark. The trial plans to enroll 15 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology