NCT06546774 The Effect of Melatonin Supplementation on Cumulus Cells and IVF Outcomes
| NCT ID | NCT06546774 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kaohsiung Veterans General Hospital. |
| Condition | Unrecognized Condition |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2021-05-01 |
| Primary Completion | 2025-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2021-05-01 with a primary completion date of 2025-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study investigates the effects of melatonin supplementation on cumulus cell gene expression and in vitro fertilization (IVF) outcomes in women over 35 years old. In the study group, patients will receive melatonin supplementation for at least two months prior to their IVF cycles. Cumulus cells will be collected after oocyte retrieval, and IVF outcomes will be assessed.
Eligibility Criteria
Inclusion Criteria: * Age 35-45 years * BMI 18-30 kg/m2 * planning to undergo IVF cycles Exclusion Criteria: * Primary ovarian insufficiency * history of oophorectomy * receiving oocyte donation * Chromosome anomaly * Congenital uterine anomaly * Severe intrauterine adhesion * Malignancy * Using hormone therapy or supplements in recent 3 months
Contact & Investigator
Kuan-Hao Tsui
STUDY DIRECTOR
Kaohsiung Veterans General Hospital.
Frequently Asked Questions
Who can join the NCT06546774 clinical trial?
This trial is open to female participants only, aged 35 Years or older, up to 45 Years, studying Unrecognized Condition. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06546774 currently recruiting?
Yes, NCT06546774 is actively recruiting participants. Contact the research team at litelin1982@gmail.com for enrollment information.
Where is the NCT06546774 trial being conducted?
This trial is being conducted at Kaohsiung City, Taiwan.
Who is sponsoring the NCT06546774 clinical trial?
NCT06546774 is sponsored by Kaohsiung Veterans General Hospital.. The principal investigator is Kuan-Hao Tsui at Kaohsiung Veterans General Hospital.. The trial plans to enroll 200 participants.