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Recruiting NCT05379673

NCT05379673 The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

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Clinical Trial Summary
NCT ID NCT05379673
Status Recruiting
Phase
Sponsor Stanford University
Condition Ventilatory Depression
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2022-10-04
Primary Completion 2026-07

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
Oxygen Gas for Inhalation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 60 participants in total. It began in 2022-10-04 with a primary completion date of 2026-07.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Eligibility Criteria

Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status I-III * Body mass index (BMI) less than 40 kg/m2 * Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy. Exclusion Criteria: * Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder * Chronic pain condition that is being treated with opioids * Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.

Contact & Investigator

Central Contact

Anthony Doufas, MD, PhD

✉ agdoufas@stanford.edu

📞 650-498-7699

Principal Investigator

Anthony Doufas, MD, PhD

PRINCIPAL INVESTIGATOR

Professor, Department of Anesthesiology, Stanford University Medical School

Frequently Asked Questions

Who can join the NCT05379673 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Ventilatory Depression. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05379673 currently recruiting?

Yes, NCT05379673 is actively recruiting participants. Contact the research team at agdoufas@stanford.edu for enrollment information.

Where is the NCT05379673 trial being conducted?

This trial is being conducted at Stanford, United States.

Who is sponsoring the NCT05379673 clinical trial?

NCT05379673 is sponsored by Stanford University. The principal investigator is Anthony Doufas, MD, PhD at Professor, Department of Anesthesiology, Stanford University Medical School. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology