NCT07320846 The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis
| NCT ID | NCT07320846 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Saglik Bilimleri Universitesi |
| Condition | Exercise |
| Study Type | INTERVENTIONAL |
| Enrollment | 39 participants |
| Start Date | 2024-05-18 |
| Primary Completion | 2025-10-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 39 participants in total. It began in 2024-05-18 with a primary completion date of 2025-10-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The main questions it aims to answer are: * Does respiratory muscle strengthening exercise added to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have additional benefits on rehabilitation outcome measures such as exercise capacity, shortness of breath, and muscle strength? * Does the gain obtained with respiratory muscle strengthening iin patients with rheumatoid arthritis-associated interstitial lung disease increase the quality of life of patients and have a positive effect on their psychological state? * Does respiratory rehabilitation applied to iin patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Does respiratory muscle strengthening training applied in addition to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Participants will be included in two different respiratory rehabilitation programs with and without respiratory muscle training, and pre- and post- treatment rehabilitation criteria and genetic changes will be compared.
Eligibility Criteria
Inclusion Criteria: * Diagnosed with RA according to the ACR/EULAR 2010 classification criteria * Duration of diagnosis greater than 2 years * Disease activity with a DAS28 score below 5.1 * Voluntary participation in the study * Presence of lung involvement Exclusion Criteria: * Having orthopedic deformities that may affect the treatment program * Pregnancy * Uncontrolled diabetes or heart disease * Participation in a rehabilitation program within the last 6 months * Body Mass Index (BMI) \> 30 * Patients with severe organ failure * Recent acute coronary syndrome * Presence of active infection
Contact & Investigator
Esra PEHLİVAN, Assoc. Prof.
STUDY CHAIR
Saglik Bilimleri Universitesi
Frequently Asked Questions
Who can join the NCT07320846 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Exercise. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07320846 currently recruiting?
Yes, NCT07320846 is actively recruiting participants. Contact the research team at zbetulozcan@gmail.com for enrollment information.
Where is the NCT07320846 trial being conducted?
This trial is being conducted at Istanbul, Turkey (Türkiye).
Who is sponsoring the NCT07320846 clinical trial?
NCT07320846 is sponsored by Saglik Bilimleri Universitesi. The principal investigator is Esra PEHLİVAN, Assoc. Prof. at Saglik Bilimleri Universitesi. The trial plans to enroll 39 participants.