NCT06923163 The Effect of Exercise on Metabolic Alteration
| NCT ID | NCT06923163 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences |
| Condition | Sedentary Behavior |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2025-05-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2025-05-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to study the effectiveness of aerobic exercise in treating obesity in adults and to assess the efficacy of exercise. The primary research questions it seeks to address are as follows: * To what extent does exercise increase the total energy expenditure of participants? * Why and how does the energy expenditure from exercise not fully compensate for the total energy expenditure (TEE)? * Researchers will assess the efficacy and potential challenges of using exercise as a treatment for obesity by comparing the measurement data before exercise intervention (week 0), immediately after exercise intervention (week 12), and 8 weeks post-completion of exercise intervention (week 20). Participants will engage in the following activities: * Engage in running sessions supervised five times a week for a duration of 12 weeks. * Attend laboratory sessions both before and after the exercise intervention period for metabolic and anthropometric measurements, as well as sample collection. * Return to the laboratory for further metabolic and anthropometric measurements and sample collection8 weeks post-completion of exercise intervention.
Eligibility Criteria
Inclusion Criteria: * Sedentary individuals * BMI ≥ 18.5 kg/m2 Exclusion Criteria: * Individuals who have undergone major surgery in the past 6 months (excluding tooth extraction); * Individuals on long-term medication; * Individuals with metabolic and cardiovascular diseases such as diabetes, hypoglycemia, and hypertension; * Individuals with exercise-related injuries, including joint diseases and fractures; * Individuals diagnosed with infectious diseases such as HIV, tuberculosis, malaria, etc.; * Individuals with mental and neurological disorders including anorexia nervosa; * Individuals who have attempted weight loss or gain through various methods in the past three months; * Individuals in preconception, pregnancy, and lactation periods; * Individuals with autism and those with metal implants in their bodies.
Contact & Investigator
John R Speakman, PhD
PRINCIPAL INVESTIGATOR
Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Frequently Asked Questions
Who can join the NCT06923163 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 40 Years, studying Sedentary Behavior. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06923163 currently recruiting?
Yes, NCT06923163 is actively recruiting participants. Contact the research team at j.speakman@abdn.ac.uk for enrollment information.
Where is the NCT06923163 trial being conducted?
This trial is being conducted at Shenzhen, China.
Who is sponsoring the NCT06923163 clinical trial?
NCT06923163 is sponsored by Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences. The principal investigator is John R Speakman, PhD at Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences. The trial plans to enroll 80 participants.