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Recruiting NCT07066605
The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation
Trial Parameters
Condition Dexmedetomidine
Sponsor Sohag University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 62
Sex ALL
Min Age 19 Years
Max Age N/A
Start Date 2025-06-13
Completion 2025-12-30
Interventions
Group A (Dexmedetomidine Group)Group B (Control Group)
Brief Summary
This study aims to evaluate the effect of dexmedetomidine on the level of agitation during the weaning process from mechanical ventilation in critically ill patients.
Eligibility Criteria
Inclusion Criteria: * Adult ICU patients (≥18 years). * On mechanical ventilation ≥24 hours. * Clinically ready for weaning. * Agitation score RASS ≥ +1 during spontaneous breathing trial. * Intubation for at least 4 days: 2 weeks. Exclusion Criteria: * Known hypersensitivity to dexmedetomidine. * Hemodynamic instability (HR \< 50 bpm or MAP \< 60 mmHg). * Neurological impairment affecting level of consciousness. * Pregnancy or lactation.
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