NCT07747181 The Effect of Combined Brain Stimulation and Yoga for Improving Cognitive Function in Psychosis
| NCT ID | NCT07747181 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Hong Kong Polytechnic University |
| Condition | Cognitive Functioning |
| Study Type | INTERVENTIONAL |
| Enrollment | 135 participants |
| Start Date | 2026-01-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 135 participants in total. It began in 2026-01-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study examines (1) the effects of active anodal (facilitatory) tDCS and yoga combined intervention on cognitive function, clinical symptoms, and quality of life domains (social function and physical wellbeing) in psychosis, and (2) the neurophysiological mechanisms underlying the effects induced by the combined intervention.
Eligibility Criteria
Inclusion Criteria: * (1) aged 18 to 65 years * (2) diagnosis based on SCID for schizophrenia and related disorders, psychosis, and delusional disorder with the positive symptom measured by CGI ≤ 3 * (3) ability to understand the nature of the study and to give informed consent (The MacArthur Competence Assessment Tool for Clinical Research score ≥ 35) * (4) Chinese-speaking * (5) fewer than 10 hours of yoga and other mind-body intervention (e.g., Tai Chi, Qigong, Mindfulness) in the previous 3 months. Exclusion Criteria: * (1) Severe physical diseases, such as myocardial infarction, uncontrollable severe hypertension, fracture, severe spinal problems, or contraindication for exercise * (2) comorbid substance dependence and seizure disorders * (3) pregnancy or other contraindication to fNIRS * (4) known history of intellectual disability or special school attendance, brain trauma, or organic brain disease * (5) Individuals taking Benzodiazepine will still be recruited in the project, and will be excluded from the fNIRS measure.
Frequently Asked Questions
Who can join the NCT07747181 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Cognitive Functioning. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07747181 currently recruiting?
Yes, NCT07747181 is actively recruiting participants. Visit ClinicalTrials.gov or contact The Hong Kong Polytechnic University to inquire about joining.
Where is the NCT07747181 trial being conducted?
This trial is being conducted at Hung Hom, Hong Kong.
Who is sponsoring the NCT07747181 clinical trial?
NCT07747181 is sponsored by The Hong Kong Polytechnic University. The trial plans to enroll 135 participants.