NCT06266182 The Effect of an Online ACT Intervention on Meaning-Making Process in Cancer Patients Following Hematopoietic Cell Transplantation
| NCT ID | NCT06266182 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Social Sciences and Humanities, Warsaw |
| Condition | Hematopoietic Cell Transplantation Recipient |
| Study Type | INTERVENTIONAL |
| Enrollment | 192 participants |
| Start Date | 2024-03-06 |
| Primary Completion | 2025-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 192 participants in total. It began in 2024-03-06 with a primary completion date of 2025-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This trial aimed to test internet-based Acceptance and Commitment Therapy (ACT) intervention to induce a meaning-making process in cancer patients following hematopoietic cell transplantation (HCT). ACT includes identifying personal values and engaging in activities consistent with these values, developing acceptance, as well as focusing on the present moment or performing activities with greater awareness. In total, 192 patients following the first (autologous or allogeneic) HCT will be randomly assigned in equal numbers to either the ACT intervention or an education session. Participants in both conditions will take part in 14-day training (about 5-10 minutes a day). The outcomes will be measured at baseline, during the intervention, immediately, 1 month, and 3 months after the intervention. Moreover, 6-9 additional participants will be randomly assigned to pre-intervention measurement length (1-3 weeks) before completing ACT intervention, followed by 7-day observations at the 2nd and 3rd post-intervention measure. The researchers hypothesized that ACT intervention would foster a meaning-making process and thus reduce distress induced by the discrepancy between global and situational meaning as compared to education.
Eligibility Criteria
Inclusion Criteria: * Qualification for the first autologous or allogeneic HCT due to hematologic malignancies or solid tumors * Age ≥ 18 years * Signed written informed consent * Ability to read and write in Polish * Daily access to the Internet by computer and/or mobile device Exclusion Criteria: * Major psychiatric or cognitive disorder that would impede providing informed consent and study participation * Inability to cooperate and give informed consent * Hearing, seeing, or movement impairment that precludes participation * Current participation in any form of psychotherapy * No access to the Internet * No access to a computer and/or mobile device * Inability to use a computer and/or mobile device and the Internet
Frequently Asked Questions
Who can join the NCT06266182 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Hematopoietic Cell Transplantation Recipient. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06266182 currently recruiting?
Yes, NCT06266182 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of Social Sciences and Humanities, Warsaw to inquire about joining.
Where is the NCT06266182 trial being conducted?
This trial is being conducted at Gliwice, Poland.
Who is sponsoring the NCT06266182 clinical trial?
NCT06266182 is sponsored by University of Social Sciences and Humanities, Warsaw. The trial plans to enroll 192 participants.