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Recruiting NCT06192199

The Diagnostic Value of APTT/Fibrinogen Ratio in Pulmonary Embolism

Trial Parameters

Condition Acute Pulmonary Embolism
Sponsor Nanfang Hospital, Southern Medical University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 800
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2018-01-01
Completion 2025-05-01
Interventions
2018 edition of the Guidelines for Diagnosis

Brief Summary

From January 1, 2023 to December 30, 2023, patients who were suspected of pulmonary embolism and underwent CTPA examination at Nanyang Hospital of Southern Medical University were divided into pulmonary embolism group and non pulmonary embolism group. 1. Collect relevant data, including gender, age, primary disease, CTPA imaging and reports, BNP, troponin, electrocardiogram, cardiac ultrasound, PT, APTT, TT, fibrinogen, D-dimer, etc., and analyze demographic data, pulmonary embolism risk grading, APTT/fibrinogen ratio, and determine their cut-off values through statistical analysis of the two groups. 2. Follow up on the APTT/fibrinogen ratio after anticoagulation treatment and bleeding in the pulmonary embolism group.

Eligibility Criteria

Inclusion Criteria: 1. Voluntary signing of informed consent form; 2. When signing the informed consent form, the age is equal to or greater than 18 years old, regardless of gender; 3. From January 1, 2023 to December 30, 2023, the patient was diagnosed with suspected pulmonary embolism at the Southern Hospital of Southern Medical University and underwent enhanced pulmonary artery scanning examination. Exclusion Criteria: 1. Patients with gastrointestinal bleeding, severe trauma, acute coronary syndrome, severe liver disease (childC grade), and coagulation dysfunction; 2. Patients with pulmonary embolism diagnosed outside the hospital and regular anticoagulation; 3. Patients undergoing regular anticoagulant therapy such as atrial fibrillation and valve replacement; 4. Patients deemed unsuitable for participation in this study by the researchers.

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