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Recruiting NCT02346435

NCT02346435 The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

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Clinical Trial Summary
NCT ID NCT02346435
Status Recruiting
Phase
Sponsor Abramson Cancer Center at Penn Medicine
Condition Kidney Neoplasm
Study Type OBSERVATIONAL
Enrollment 600 participants
Start Date 2009-01
Primary Completion 2028-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 100 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 600 participants in total. It began in 2009-01 with a primary completion date of 2028-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.

Eligibility Criteria

Inclusion Criteria: * Must have a solid, enhancing renal mass ≤4cm at its greatest dimension found on incidental scanning in the last 6 months. * Age ≥ 18 and able to read, understand and sign informed consent. * Must be willing to adhere to the treatment algorithm and time constraints therein. Exclusion Criteria: * Cannot have suspicion of metastases to the kidney if any other malignancy diagnosed within two years of study entry.

Contact & Investigator

Central Contact

Nirmish Singla

✉ nsingla2@jhmi.edu

📞 410-502-3692

Principal Investigator

Mohamad E Allaf, MD, MBA

PRINCIPAL INVESTIGATOR

Johns Hopkins University

Frequently Asked Questions

Who can join the NCT02346435 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Kidney Neoplasm. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT02346435 currently recruiting?

Yes, NCT02346435 is actively recruiting participants. Contact the research team at nsingla2@jhmi.edu for enrollment information.

Where is the NCT02346435 trial being conducted?

This trial is being conducted at Baltimore, United States.

Who is sponsoring the NCT02346435 clinical trial?

NCT02346435 is sponsored by Abramson Cancer Center at Penn Medicine. The principal investigator is Mohamad E Allaf, MD, MBA at Johns Hopkins University. The trial plans to enroll 600 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology