The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy
Trial Parameters
Brief Summary
To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal mucoperiosteal flap, promoting wound healing, forming a good anastomosis, preventing postoperative anastomosis and shortening operation time. Twenty patients with chronic dacryocystitis were randomly divided into photosensitive hydrogel group and suture group.Symptoms and nasal endoscopy were followed up 2, 6, and 12 weeks after surgery for both groups. And also adverse events were recorded at each follow-up.
Eligibility Criteria
Inclusion Criteria: 1. Voluntarily participate in this clinical study and sign the informed consent; 2. Gender is not limited, age 18-75 years old; 3. The patient had symptoms and signs of chronic dacryocystitis, and the results of lacrimal passage irrigation suggested that the lower rush and return or upper rush and lower return, accompanied by mucous or purulent discharge reflux; 4. Lacrimal duct angiography suggests nasolacrimal duct obstruction without lacrimal canaliculi and/or duct obstruction. Exclusion Criteria: 1. Age \< 18 or \> 75 years old; 2. Previous history of dacryocystonasal anastomosis; 3. Abnormal coagulation function; 4. Tumors of lacrimal passage, especially in patients with papilloma or malignant tumors; 5. in the acute dacryocystitis attack stage; 6. obvious scar constitution; 7. Complicated with serious nasal diseases, such as severe allergic rhinitis, chronic rhinosinusitis and nasal polyps, acute suppurative rhinosinusitis, severe atrophic rhinitis, and severe