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Recruiting NCT06795893

NCT06795893 The Anifrolumab PRIM Program

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Clinical Trial Summary
NCT ID NCT06795893
Status Recruiting
Phase
Sponsor AstraZeneca
Condition Systemic Lupus Erythematosus
Study Type OBSERVATIONAL
Enrollment 240 participants
Start Date 2025-11-07
Primary Completion 2031-04-15

Trial Parameters

Condition Systemic Lupus Erythematosus
Sponsor AstraZeneca
Study Type OBSERVATIONAL
Phase N/A
Enrollment 240
Sex FEMALE
Min Age N/A
Max Age N/A
Start Date 2025-11-07
Completion 2031-04-15
Interventions
Anifrolumab

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Brief Summary

Pregnancy and infant outcomes in anifrolumab exposed pregnancies using PRegnancy outcomes Intensive Monitoring (PRIM) data: The anifrolumab PRIM program

Eligibility Criteria

Inclusion Criteria: * Currently or recently (within 1 year of pregnancy outcome) pregnant * Exposure to at least 1 dose of anifrolumab at any time during pregnancy or in the 16 weeks prior to date of conception Exclusion Criteria: * Pregnancy cases that have been enrolled in the prospective pregnancy registry (D3461R00051), those reported prior to the start of the PRIM program, or those that have been exposed to known teratogens or investigational medications will be excluded from the anifrolumab PRIM study.

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