NCT07431710 The AIR-CPR Study: AI-Guided Chest Compressions
| NCT ID | NCT07431710 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Far Eastern Memorial Hospital |
| Condition | Out-of-hospital Cardiac Arrest (OHCA) |
| Study Type | OBSERVATIONAL |
| Enrollment | 255 participants |
| Start Date | 2025-01-06 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 255 participants in total. It began in 2025-01-06 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations. Current guidelines recommend a standardized compression point (the lower half of the sternum), yet recent research indicates that this position can compress the aortic valve in approximately 48.7% of patients, significantly reducing the chances of successful resuscitation. This study will develop a deep learning model based on YOLO v8 to analyze real-time arterial pressure waveforms to identify proper aortic valve opening and closing. By identifying specific waveform features that humans cannot easily distinguish, the AI will guide rescuers to adjust the compression site-typically toward the left ventricle-to ensure optimal blood output. The project seeks to transform CPR from a standardized "one-size-fits-all" approach into a personalized, precision medicine intervention.
Eligibility Criteria
Inclusion Criteria: 1. Adults aged 20 years or older. 2. Patients with out-of-hospital cardiac arrest (OHCA) undergoing 3.cardiopulmonary resuscitation (CPR) in the emergency department. Cardiac arrest caused by non-traumatic factors. Exclusion Criteria: 1. Pregnant patients. 2. Patients with obvious signs of death. 3. Patients with a signed "Do Not Resuscitate" (DNR) order. 4. Patients requiring extracorporeal cardio-pulmonary resuscitation (ECPR). 5. Patients requiring Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA). 6. Cardiac arrest caused by massive hemorrhage, aortic emergencies, tension pneumothorax, cardiac tamponade, or pulmonary embolism. 7. History of severe aortic valve disease or previous aortic valve surgery. 8. Patients for whom TEE or femoral arterial catheterization is contraindicated. 9. Situations where the medical team is unable to perform TEE or femoral arterial catheterization during CPR.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07431710 clinical trial?
This trial is open to participants of all sexes, aged 20 Years or older, studying Out-of-hospital Cardiac Arrest (OHCA). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07431710 currently recruiting?
Yes, NCT07431710 is actively recruiting participants. Contact the research team at ianchu300@msn.com for enrollment information.
Where is the NCT07431710 trial being conducted?
This trial is being conducted at New Taipei City, Taiwan.
Who is sponsoring the NCT07431710 clinical trial?
NCT07431710 is sponsored by Far Eastern Memorial Hospital. The trial plans to enroll 255 participants.