Trial Parameters
Condition Respiratory Support
Sponsor Unity Health Toronto
Study Type OBSERVATIONAL
Phase N/A
Enrollment 30
Sex ALL
Min Age 16 Years
Max Age N/A
Start Date 2021-12-17
Completion 2026-06
Interventions
Mechanical Ventilation
Brief Summary
The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.
Eligibility Criteria
Inclusion Criteria: * Presence of traumatic spine lesion (with and without spinal cord injury) * Requiring invasive mechanical ventilation, via oro-tracheal or tracheostomy tube, * 16 years of age or older * Patient or substitute decision maker able to provide consent Exclusion Criteria: * Expected withdrawal of treatments within 24 hours of screening * Chronic respiratory failure already treated with mechanical ventilation before the injury * Documented pre-existing neuromuscular diseases