NCT06498817 Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)
| NCT ID | NCT06498817 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johns Hopkins Bloomberg School of Public Health |
| Condition | Diarrhea Infectious |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,600 participants |
| Start Date | 2024-08-19 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,600 participants in total. It began in 2024-08-19 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The findings from previous recent randomized controlled trials of The Cholera Hospital Based Intervention for 7 Days (CHoBI7) demonstrated that this intervention was effective in significantly reducing symptomatic cholera infections, diarrheal disease, and stunting among young children in intervention households, and had significant sustained impacts on handwashing with soap behaviors and improved water quality 12 months post intervention. Therefore, the investigators next step in the transition to scale is to: (1) To tailor the CHoBI7 program for delivery in rural health facilities and market test the CHoBI7 Program to determine the feasibility of providing a modified water, sanitation, and hygiene (WASH) package with only a soapy water bottle and chlorine tablets in both urban and rural settings through formative research and engagement of key stakeholders (Formative Research Phase); and (2) To evaluate the effectiveness of delivering the CHoBI7 program in district hospitals and sub-district health complexes in rural areas in terms of increases in WASH behaviors and decreases in diarrheal disease by conducting a randomized controlled trial (RCT) (Intervention Implementation and Evaluation Phase).
Eligibility Criteria
Inclusion Criteria: * Diarrhea patients presenting with three or more loose stools over a 24h period * Having no running water inside of the patient's home * Plan to reside in current residence for the next 3 months * Have a child \<5 years in the patient's household * Have a working mobile phone in the household Exclusion Criteria: * No one will be excluded because of age, sex, religion, or sexual preference
Contact & Investigator
Christine Marie George, PhD
PRINCIPAL INVESTIGATOR
Johns Hopkins Bloomberg School of Public Health
Frequently Asked Questions
Who can join the NCT06498817 clinical trial?
This trial is open to participants of all sexes, studying Diarrhea Infectious. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06498817 currently recruiting?
Yes, NCT06498817 is actively recruiting participants. Contact the research team at cmgeorge@jhu.edu for enrollment information.
Where is the NCT06498817 trial being conducted?
This trial is being conducted at Mānikganj, Bangladesh.
Who is sponsoring the NCT06498817 clinical trial?
NCT06498817 is sponsored by Johns Hopkins Bloomberg School of Public Health. The principal investigator is Christine Marie George, PhD at Johns Hopkins Bloomberg School of Public Health. The trial plans to enroll 1,600 participants.