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Recruiting NCT07107386

NCT07107386 Temporal Investigation of Multimodal Elements

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Clinical Trial Summary
NCT ID NCT07107386
Status Recruiting
Phase
Sponsor Buck Institute for Research on Aging
Condition Health
Study Type OBSERVATIONAL
Enrollment 120 participants
Start Date 2025-06-15
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age 55 Years
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

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What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 120 participants in total. It began in 2025-06-15 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The TIME Study is a research project aiming to understand the body's natural rhythms. The goal is to see how daily and weekly changes in our bodies-from what's happening at a molecular level to data from wearable devices-are connected. What is the study about? This study is trying to create a detailed map of how a person's body changes over time. By looking at information from blood, urine, and other samples, as well as data from smartwatches and other devices, researchers want to learn how our bodies' natural cycles work in healthy older adults. The long-term goal is to use this knowledge to help develop more personalized healthcare in the future. Who can participate? The study is looking for healthy adults, age 55 or older, who have a smartphone and are able to travel to the Buck Institute in Novato, California, for study visits. Participants will be asked to: Attend weekly visits over 11 weeks to provide blood and other samples. Wear health-tracking devices like a smart ring and watch. Use a smartphone app to answer questions about their daily routines. Complete two "challenge" tests, including drinking a glucose solution and exercising on a stationary bicycle. Return for follow-up visits after 6 and 12 months. Are there any risks or benefits? Benefits: There are no direct health benefits for participants. However, the information gained will help scientists create better diagnostic tools and treatments for future generations. Risks: The main risks are minor discomfort from things like blood draws or skin irritation from the wearable devices. All personal information and data are kept private and secure.

Eligibility Criteria

Inclusion Criteria: * Healthy adults aged 55 years or older. * Own a smartphone capable of running study-specific apps. * Willing and able to attend in-person visits at the Buck Institute in Novato, CA. * Reside in the Pacific or Mountain Time Zones. * Able to speak, read, and write English. * Willing to wear study devices continuously and allow researchers access to all data. * Able to provide informed consent. Exclusion Criteria: * Hospitalization within the last 3 months. * Needing assistance with daily living activities. * Working night or irregular shifts. * Certain musculoskeletal, pulmonary, or cardiovascular conditions. * Uncontrolled high blood pressure (BP \> 180/100 mmHg). * Bleeding disorders, anemia requiring treatment, or recent blood donation. * Poor vein access. * Unstable health conditions. * Chronic antibiotic use. * Certain psychiatric disorders. * Use of excluded medications, supplements, or products, including certain antibiotics or frequent sleep aids.

Contact & Investigator

Central Contact

Brianna Stubbs, Research Assistant Professor, PhD.

✉ TIME-Study@buckinstitute.org

📞 (415) 209-2072

Principal Investigator

James Yurkovich, PhD

PRINCIPAL INVESTIGATOR

Phenome Health, The Buck Institute for Research on Aging

Frequently Asked Questions

Who can join the NCT07107386 clinical trial?

This trial is open to participants of all sexes, aged 55 Years or older, studying Health. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07107386 currently recruiting?

Yes, NCT07107386 is actively recruiting participants. Contact the research team at TIME-Study@buckinstitute.org for enrollment information.

Where is the NCT07107386 trial being conducted?

This trial is being conducted at Novato, United States.

Who is sponsoring the NCT07107386 clinical trial?

NCT07107386 is sponsored by Buck Institute for Research on Aging. The principal investigator is James Yurkovich, PhD at Phenome Health, The Buck Institute for Research on Aging. The trial plans to enroll 120 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology