NCT07884500 Temporal Dynamics of Peripheral SpO₂ During Reoxygenation
| NCT ID | NCT07884500 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
| Condition | Healthy Vollunteer |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-08-03 |
| Primary Completion | 2027-02-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-08-03 with a primary completion date of 2027-02-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Pulse oximeters estimate arterial oxyhaemoglobin saturation (SaO₂) from photoplethysmographic signals recorded at peripheral sites (usually the fingertip), thus measuring the peripheral oxygen saturation (SpO₂). They are ubiquitous in emergency medicine because they offer a non-invasive, continuous measure of oxygenation and can alert clinicians to impending hypoxaemia, both during procedures such as rapid sequence intubation or sedation, or for continuous monitoring of patients. However, the accuracy of SpO₂ is often assumed to be instantaneous. This assumption is particularly hazardous during critical events involving rapid desaturation and resaturation. In such situations clinicians use SpO₂ readings to decide when to stop an apnea period during laryngoscopy and commence reoxygenation. If there is a delay between actual arterial desaturation and the displayed SpO₂, the clinician may not recognise hypoxaemia in time or may resume ventilation too late.
Eligibility Criteria
Inclusion Criteria: * Healthy adult volunteers aged 18 to 60 years * Able to perform voluntary apnea for at least 30 seconds * Written informed consent, read and signed by the participant Exclusion Criteria: * History of chronic respiratory, cardiac, or hematological disease * Recent respiratory infection (\< 2 weeks) * Use of vasoactive medications (e.g., beta-blockers, vasodilators) * Known or suspected pregnancy * Inability to understand the study information or follow the study instructions * Refusal to participate or withdrawal of consent
Frequently Asked Questions
Who can join the NCT07884500 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Healthy Vollunteer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07884500 currently recruiting?
Yes, NCT07884500 is actively recruiting participants. Visit ClinicalTrials.gov or contact Cliniques universitaires Saint-Luc- Université Catholique de Louvain to inquire about joining.
Where is the NCT07884500 trial being conducted?
This trial is being conducted at Brussels, Belgium.
Who is sponsoring the NCT07884500 clinical trial?
NCT07884500 is sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain. The trial plans to enroll 100 participants.