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Recruiting NCT07425756

taVNS Combined With TENS on Motor Function in Stroke

Trial Parameters

Condition Stroke
Sponsor The Hong Kong Polytechnic University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 120
Sex ALL
Min Age 50 Years
Max Age 75 Years
Start Date 2025-01-01
Completion 2027-12-01
Interventions
transcutaneous auricular vagus nerve stimulationsham transcutaneous auricular vagus nerve stimulationtranscutaneous electrical nerve stimulation

Brief Summary

the current study is a Blinded Randomised Controlled Trial investing the effectiveness of Combining Transcutaneous Vagus Nerve Stimulation with Peripheral Nerve Stimulation on Upper Limb Motor Function in People with Stroke

Eligibility Criteria

Inclusion Criteria: 1. aged 55 - 75 years old; 2. diagnosed with stroke confirmed by magnetic resonance imaging or computed tomography for more than 6 months; 3. had volitional control of the non-paretic arm and at least minimal antigravity movement in the paretic shoulder; 4. had at least 5 degrees of wrist extension in the antigravity position; 5. be able to communicate Exclusion Criteria: 1. had neurological disease other than stroke, e.g., Parkinson's disease or dementia; 2. ongoing healthy condition, e.g., angina pectoris, pain, or arthritis; 3. had any contraindications of taVNS (metal implants in the brain, history of seizure)

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