NCT05131035 Targeting Processing Speed Deficits to Improve Social Functioning and Lower Psychosis Risk
| NCT ID | NCT05131035 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Northwell Health |
| Condition | Psychosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2021-10-28 |
| Primary Completion | 2026-05-31 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
This 10 week intervention, Specific Cognitive Remediation with Surround (or SCORES), is designed to target processing speed, a cognitive domain related directly to social functioning, which in turn, represents a vulnerability factor for psychosis. This remotely-delivered intervention combining targeted cognitive training exercises and group support was developed to directly impact processing speed, and at the same time, boost motivation and engagement in adolescents at risk for schizophrenia and other psychotic disorders.
Eligibility Criteria
Inclusion Criteria: * Meet Clinical High Risk (CHR) criteria on the Structured Interview for Psychosis Risk Syndromes, defined by the presence of at least one attenuated positive symptom at a moderate to severe level * A score representing 0.5 SD below the mean on Animal Naming, Trails A or BACS: Symbol Coding from the MATRICS Consensus Cognitive Battery (MCCB). Exclusion Criteria: * Any DSM 5 Schizophrenia-Spectrum diagnosis * Non-English speaking * Past or current history of a clinically significant central nervous system disorder (e.g., seizure disorder) * Estimated IQ\<70 * Significant head injury * Significant substance abuse * Significant visual or auditory impairment.