NCT07079254 Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
| NCT ID | NCT07079254 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Region Skane |
| Condition | Meniscus Rupture |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2023-10-07 |
| Primary Completion | 2035-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2023-10-07 with a primary completion date of 2035-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces. In doing so, it helps protect the joint from osteoarthritis - a form of joint failure commonly referred to as "joint wear". Meniscal surgeries are among the most common orthopaedic procedures performed both in Sweden and globally. Historically, damaged menisci were treated by removing the injured part. However, this approach is linked to early-onset osteoarthritis. Osteoarthritis affects approximately one-third of individuals over the age of 45 and ranks among the ten most common diagnoses in Europe based on years lived with disability. The knee is the most frequently affected joint, and the importance of the menisci in preserving knee function has become increasingly recognized. In recent years, advances in surgical techniques have led to a shift towards meniscus-preserving procedures. A typical injury is the displaced meniscus, in which a large portion of the meniscus becomes detached from the joint capsule and wedges itself inside the joint, causing mechanical locking and preventing full extension. A displaced meniscus often loses its blood supply and suffers mechanical damage from being compressed between the joint surfaces. To preserve the meniscus and prevent irreversible damage, early surgical intervention is required. If the injury is too old or the tissue too damaged, the injured part of the meniscus must be removed, which significantly increases the risk of developing early knee osteoarthritis. It remains unclear how soon surgery must be performed to successfully preserve the meniscus, and this likely depends on various other factors, including patient age, presence of additional joint injuries, and surgical technique. There is currently no reliable data on the proportion of displaced menisci that heal after meniscus-preserving surgery. However, studies suggest that 20-30% of repaired menisci require reoperation due to failed healing. Given that displaced menisci are considered surgical emergencies, they pose a significant burden on healthcare systems already strained by limited access to urgent surgery. Meanwhile, ongoing development of surgical techniques raise ethical and logistical questions for health providers - especially as the scientific evidence for the benefits of some advanced treatments remains inconclusive. Therefore, more research is needed to guide the optimal management of displaced bucket-handle lesions across a diverse patient population, taking into account age, activity level, and concurrent injuries. A key priority is to identify predictors of healing potential, particularly the time window during which surgical repair remains a viable option. With better knowledge, more menisci could potentially be preserved - reducing both the number of unnecessary re-operations and the long-term incidence of knee osteoarthritis.
Eligibility Criteria
Inclusion Criteria: * 15 years or above. * Displaced longitudinal bucket-handle tear including the posterior horn on MRI and a knee extension deficit. Exclusion Criteria: * Patient younger than 15 years. * Insufficient knowledge of the Swedish language. * Per-operative findings including a bucket-handle rupture in combination with a complete radial rupture
Contact & Investigator
Ola Svejme, MD, PhD
PRINCIPAL INVESTIGATOR
Lund University, Department of Orthopaedics, Clinical Sciences, Malmö, Sweden
Frequently Asked Questions
Who can join the NCT07079254 clinical trial?
This trial is open to participants of all sexes, aged 15 Years or older, studying Meniscus Rupture. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07079254 currently recruiting?
Yes, NCT07079254 is actively recruiting participants. Contact the research team at sofie.alerskans@med.lu.se for enrollment information.
Where is the NCT07079254 trial being conducted?
This trial is being conducted at Hässleholm, Sweden, Malmö, Sweden.
Who is sponsoring the NCT07079254 clinical trial?
NCT07079254 is sponsored by Region Skane. The principal investigator is Ola Svejme, MD, PhD at Lund University, Department of Orthopaedics, Clinical Sciences, Malmö, Sweden. The trial plans to enroll 300 participants.