NCT06268262 Surgical-imaging Research on Obesity (SIRO)
| NCT ID | NCT06268262 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The Affiliated Hospital of Xuzhou Medical University |
| Condition | Overweight and Obesity |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2023-03-01 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2023-03-01 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The global obesity epidemic is well established, and is an important public health issue. The previous researches had applied the clues that obesity is a kind of systemic disease. The investigators hypothesized that a serious alteration of the body systems will occur after bariatric surgery, which may shed light on the mechanisms of obesity. Thus, the research aims to combine the imaging and surgery to investigate the alterations of the body that induced by obese and alterations after surgery.
Eligibility Criteria
Inclusion Criteria for obesity group: Meeting the obesity criteria (BMI \> 28); 2) Meeting the indications for bariatric surgery, planning to undergo surgery for the first time; 3) Age between 18-65 years old, no gender restrictions; 4) Right-handed, of Han ethnicity; 5) Informed consent to the study, willing to cooperate with the research, and able to sign an informed consent form. Inclusion Criteria for the Control Group: 1. Healthy volunteers with a BMI between 18.5-23.9; 2. Age between 18-65 years old, no gender restrictions; 3. Right-handed, of Han ethnicity; 4. Informed consent to the study, willing to cooperate with the research, and able to sign an informed consent form. Exclusion Criteria for obesity group: 1. Secondary obesity caused by other organic diseases or medication (such as hormone use, etc.); 2. Unable to undergo surgery as planned; 3. Pregnant or breastfeeding; 4. Low cognitive ability and incapable of cooperating with the study; 5. Eating disorders; 6. Alcohol or drug dependence; 7. Meeting the criteria for organic mental disorders, severe mental disorders (schizophrenia, etc.), or other serious mental illnesses requiring clinical intervention; 8. Contraindications for MR scanning (pacemakers, cochlear implants, metal objects in the body, claustrophobia, weight exceeding the machine's load limit, etc.); 9. History of neurological organic diseases (brain tumors, epilepsy, cerebrovascular accidents, severe head trauma, etc.); 10. History of congenital heart disease (myocardial infarction, severe arrhythmias, heart failure, cardiomyopathy, rheumatic heart disease, congenital heart disease, etc.); 11. Severe liver, kidney, lung, digestive dysfunction, endocrine, and blood system diseases; 12. Active infections within the last two weeks (fever, upper respiratory infection, acute gastroenteritis, etc.); 13. Use of drugs affecting the nervous system or psychotropic drugs within the last six months. Exclusion Criteria for the Control Group: The same criteria as points 3) to 13) above.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06268262 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Overweight and Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06268262 currently recruiting?
Yes, NCT06268262 is actively recruiting participants. Contact the research team at liu-k@hotmail.com for enrollment information.
Where is the NCT06268262 trial being conducted?
This trial is being conducted at Xuzhou, China.
Who is sponsoring the NCT06268262 clinical trial?
NCT06268262 is sponsored by The Affiliated Hospital of Xuzhou Medical University. The trial plans to enroll 200 participants.
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