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Recruiting NCT05845021

NCT05845021 Surgeon-Initiated Bone Health Referral Pathway in Patients Undergoing Lower Extremity Arthroplasty

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Clinical Trial Summary
NCT ID NCT05845021
Status Recruiting
Phase
Sponsor Johns Hopkins University
Condition Osteoporosis
Study Type INTERVENTIONAL
Enrollment 2,000 participants
Start Date 2023-09-27
Primary Completion 2027-10

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Surgeon-Initiated Bone Health Referral Pathway

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 2,000 participants in total. It began in 2023-09-27 with a primary completion date of 2027-10.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this clinical trial is to observe the impact of a surgeon-driven bone health referral pathway following lower extremity arthroplasty. The main question this study aims to answer is: 1\) What is impact of a surgeon-driven bone health referral pathway on implant-related complications and fragility fractures when compared to standard of care primary care provider referral. Researchers will compare the endocrinology referral pathway and standard of care to see if there is a difference in treatment rates, fragility fractures, and implant-related complications following lower extremity arthroplasty.

Eligibility Criteria

Inclusion Criteria: * \>50 * DEXA-confirmed diagnosis of osteoporosis Exclusion Criteria: * Prior diagnosis of osteoporosis * Prior treatment for osteoporosis

Contact & Investigator

Central Contact

Savyasachi C Thakkar, MD

✉ sthakka2@jhmi.edu

📞 443-997-2663

Principal Investigator

Savyasachi Thakkar, MD

PRINCIPAL INVESTIGATOR

Johns Hopkins School of Medicine

Frequently Asked Questions

Who can join the NCT05845021 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, studying Osteoporosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05845021 currently recruiting?

Yes, NCT05845021 is actively recruiting participants. Contact the research team at sthakka2@jhmi.edu for enrollment information.

Where is the NCT05845021 trial being conducted?

This trial is being conducted at Columbia, United States.

Who is sponsoring the NCT05845021 clinical trial?

NCT05845021 is sponsored by Johns Hopkins University. The principal investigator is Savyasachi Thakkar, MD at Johns Hopkins School of Medicine. The trial plans to enroll 2,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology