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Recruiting NCT04933266

NCT04933266 Subpectoral Plexus Block With Multi-level TPVB for Surgical Anesthesia During Primary Breast Cancer Surgery

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Clinical Trial Summary
NCT ID NCT04933266
Status Recruiting
Phase
Sponsor Chinese University of Hong Kong
Condition Breast Cancer
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2024-03-15
Primary Completion 2026-03-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 80 Years
Study Type INTERVENTIONAL
Interventions
Subpectoral plexus block (low dose)Subpectoral plexus block (High dose)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2024-03-15 with a primary completion date of 2026-03-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The objective of this study is to compare two different doses of local anesthetics (10ml vs 20ml of 0.25% levobupivacaine) for subpectoral plexus block (SPPB) in addition to ultrasound guided multi-level of thoracic paravertebral block (m-TPVB) for surgical anaesthesia for major primary breast cancer surgery.

Eligibility Criteria

Inclusion Criteria: * scheduled for mastectomy, modified radical mastectomy or breast conservative surgery with lymph node biopsy and with or without axillary dissection Exclusion Criteria: * local skin site infection * coagulopathy * history of allergy to local anesthetics

Contact & Investigator

Central Contact

Ayla Wong, RN, BN

✉ aylawong@cuhk.edu.hk

📞 3505 6157

Principal Investigator

Manoj K Karmakar, MD

PRINCIPAL INVESTIGATOR

Chinese University of Hong Kong

Frequently Asked Questions

Who can join the NCT04933266 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Breast Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04933266 currently recruiting?

Yes, NCT04933266 is actively recruiting participants. Contact the research team at aylawong@cuhk.edu.hk for enrollment information.

Where is the NCT04933266 trial being conducted?

This trial is being conducted at Sheung Shui, Hong Kong.

Who is sponsoring the NCT04933266 clinical trial?

NCT04933266 is sponsored by Chinese University of Hong Kong. The principal investigator is Manoj K Karmakar, MD at Chinese University of Hong Kong. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology