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Recruiting Phase 1 NCT05873699

Study Using Hyperpolarized 13C-Pyruvate Magnetic Resonance Spectroscopic Imaging in Patients With Pancreatic Cysts Undergoing Surgical Resection

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Plain-language summary for patients

Trial Parameters

Condition Pancreatic Cyst
Sponsor M.D. Anderson Cancer Center
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 20
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2023-08-18
Completion 2027-01-31
Interventions
Hyperpolarized 13-C-pyruvate

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Brief Summary

To learn if Hyperpolarized C-Pyruvate Magnetic Resonance (HP-MR) Spectroscopic Imaging can help doctors detect low-risk (benign) and high-risk (malignant) cysts.

Eligibility Criteria

Inclusion Criteria: * Patients ≥ 18 years old. Patients under 18 are excluded due to their potential inability to understand and consent independently to the methods required for the study drug use and its potential risks and benefits. * Patients with pancreatic cyst/s * Patients who will undergo surgical resection (or cyst wall biopsy) of pancreatic cysts * Patients able to understand and willing to sign a written informed consent document * Both English-speaking and non-English-speaking patients are eligible for participation Exclusion Criteria: * Contraindication to MRI * Electrically, magnetically, or mechanically activated implants that would preclude MRI * Allergy to Gadavist IV contrast * History of cardiac arrhythmias * Pregnancy or breastfeeding women * Women of child-bearing age that are sexually active and not using birth control * Cognitively impaired individuals * Weight above 260 pounds (lbs)

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