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Recruiting NCT07285356

Study to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy

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Trial Parameters

Condition Colon Cancer
Sponsor AC Camargo Cancer Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 84
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-10-06
Completion 2026-09-18
Interventions
Surgical Gloves

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Brief Summary

The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.

Eligibility Criteria

Inclusion Criteria: * Patients aged 18 years or older who have provided written informed consent. * Colon adenocarcinoma with high-risk stage III (pT4pN2) or stage IV. * Oxaliplatin-based treatment in the context of localized or metastatic disease. * Eastern Cooperative Oncology Group (ECOG) performance status of 0-1. Exclusion Criteria: * Pre-existing neuropathy. * Uncontrolled diabetes. * known glove allergies. * Prior treatment with paclitaxel, docetaxel or oxaliplatin.

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