NCT06414967 Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
| NCT ID | NCT06414967 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Poitiers University Hospital |
| Condition | Huntington Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 15 participants |
| Start Date | 2024-10-15 |
| Primary Completion | 2026-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 15 participants in total. It began in 2024-10-15 with a primary completion date of 2026-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease. This pilot study aims to show the interest of alternative non-pharmacological measures such as a digital music therapy tool, adapted to an audience of Huntington's patients, to help manage the psychobehavioral symptoms frequently observed in this affection, and to avoid breakdowns due to caregiver exhaustion.
Eligibility Criteria
Inclusion Criteria: * Age \>= 18 years * Huntington disease genetically confirmed by the presence of at least 35 repeats of the CAG triplet in exon 1 of the HTT gene * UHDRS (Unified Huntington's disease Rating Scale) score \<= 5 with a diagnostic confidence score =4 * Absence of significant cognitive impairment MoCA \>=24 * Stable drug therapy in the 28 days prior inclusion and during the study * Without legal tutors or subordination * Affiliated to a health insurance system as required by the French law on biomedical research * Written informed consent for participation in the study Exclusion Criteria: * Inability to give free and informed consent for study participation * Significant hearing impairment * Participating to another study the day of enrollement * Persons benefiting from enhanced protection, i.e.persons deprived of their liberty by a judicial or administrative decision, adults under legal and finally patients in a vital emergency situation.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06414967 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Huntington Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06414967 currently recruiting?
Yes, NCT06414967 is actively recruiting participants. Contact the research team at isabelle.benatru@chu-poitiers.fr for enrollment information.
Where is the NCT06414967 trial being conducted?
This trial is being conducted at Poitiers, France.
Who is sponsoring the NCT06414967 clinical trial?
NCT06414967 is sponsored by Poitiers University Hospital. The trial plans to enroll 15 participants.