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Recruiting Phase 2, Phase 3 NCT07378527

NCT07378527 Study of the Efficacy and Safety of ICP-332 in Participants With Chronic Spontaneous Urticaria

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Clinical Trial Summary
NCT ID NCT07378527
Status Recruiting
Phase Phase 2, Phase 3
Sponsor Beijing InnoCare Pharma Tech Co., Ltd.
Condition Chronic Spontaneous Urticaria (CSU)
Study Type INTERVENTIONAL
Enrollment 344 participants
Start Date 2026-02-13
Primary Completion 2028-09

Trial Parameters

Condition Chronic Spontaneous Urticaria (CSU)
Sponsor Beijing InnoCare Pharma Tech Co., Ltd.
Study Type INTERVENTIONAL
Phase Phase 2, Phase 3
Enrollment 344
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2026-02-13
Completion 2028-09
Interventions
ICP-332 TabletsICP-332 placebo TabletsICP-332 Tablets

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Brief Summary

The purpose of this study is to compare the efficacy and safety of ICP-332 in moderate to severe chronic spontaneous urticaria subjects inadequately controlled by second generation H1-antihistamines

Eligibility Criteria

Inclusion Criteria: * 1\. Men and women aged 18 to 75 years. * 2\. Diagnosis of CSU inadequately controlled by second generation H1-antihistamines. * 3\. CSU duration for ≥ 6 months prior to randomization. * 4\. Before initiating any screening or study-specific procedures, the subject must voluntarily sign the informed consent form. Exclusion Criteria: * 1\. Having the other medical conditions related to CSU or other skin diseases/conditions. * 2\. Potential medical conditions or issues. * 3\. Pregnant female subjects or lactating female subjects. * 4\. The investigator determines that the subject is unsuitable for participating in this study for any reason.

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