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Recruiting NCT07334457

Study of Platelet Population Changes Under Circulatory Support With ECMO

Trial Parameters

Condition Cardiac Failure
Sponsor University Hospital, Strasbourg, France
Study Type OBSERVATIONAL
Phase N/A
Enrollment 75
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-03-11
Completion 2027-03

Brief Summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Eligibility Criteria

Inclusion Criteria: * Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital. * Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours. Exclusion Criteria: * Subject who has expressed their opposition to participating in the study. * Subject under legal protection. * Subject under guardianship or curatorship.

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