NCT05303415 Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals
| NCT ID | NCT05303415 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Virginia Polytechnic Institute and State University |
| Condition | Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2022-05-06 |
| Primary Completion | 2027-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2022-05-06 with a primary completion date of 2027-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Study of LIFU on fMRI pain signals. Participants receive low-intensity focused ultrasound (LIFU) and fMRI scans to measure changes in both resting and heat pain signals. Physiology may also be measured. Questionnaires and symptom monitoring will take place. The study takes place over 4 study visits.
Eligibility Criteria
Inclusion Criteria: * Healthy volunteers, all ethnicities, who understand and speak English. Exclusion Criteria: Claustrophobia (scanning environment may be uncomfortable). Contraindications to MRI: including pacemaker, aneurysm clips, neurostimulators, cochlear implants, metal in eyes, steel worker, or other implants. Contraindications to CT: pregnancy Active medical disorder or treatment with potential CNS effects (e.g. Alzheimer's) History of neurologic disorder. (e.g. Parkinson's, Epilepsy, or Essential Tremor) History of head injury resulting in loss of consciousness for \>10 minutes. History of alcohol or drug dependence (through self-report).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05303415 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05303415 currently recruiting?
Yes, NCT05303415 is actively recruiting participants. Contact the research team at legonlab@vtc.vt.edu for enrollment information.
Where is the NCT05303415 trial being conducted?
This trial is being conducted at Roanoke, United States.
Who is sponsoring the NCT05303415 clinical trial?
NCT05303415 is sponsored by Virginia Polytechnic Institute and State University. The trial plans to enroll 80 participants.