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Recruiting Phase 2 NCT07616128

NCT07616128 Study of EVO756 in Adults With Migraine

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Clinical Trial Summary
NCT ID NCT07616128
Status Recruiting
Phase Phase 2
Sponsor Evommune, Inc.
Condition Migraine
Study Type INTERVENTIONAL
Enrollment 330 participants
Start Date 2026-07-29
Primary Completion 2027-10

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 64 Years
Study Type INTERVENTIONAL
Interventions
EVO756, Dose 1EVO756, Dose 2Placebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 330 participants in total. It began in 2026-07-29 with a primary completion date of 2027-10.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.

Eligibility Criteria

Key Inclusion Criteria: * Adults aged 18 to \<65 years * Migraine with or without aura, per ICHD-3 criteria * History of failure with prior preventive migraine treatments * Not currently using migraine preventive therapy Key Exclusion Criteria: * Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders * Use of certain medications * Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities

Contact & Investigator

Central Contact

Nichole Baio

✉ nichole.baio@evommune.com

📞 (650) 319-4553

Frequently Asked Questions

Who can join the NCT07616128 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 64 Years, studying Migraine. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07616128 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07616128 currently recruiting?

Yes, NCT07616128 is actively recruiting participants. Contact the research team at nichole.baio@evommune.com for enrollment information.

Where is the NCT07616128 trial being conducted?

This trial is being conducted at Chandler, United States, Buena Park, United States, Fresno, United States, Los Angeles, United States and 11 additional locations.

Who is sponsoring the NCT07616128 clinical trial?

NCT07616128 is sponsored by Evommune, Inc.. The trial plans to enroll 330 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology