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Recruiting NCT06016569

NCT06016569 Study of Early Cancer Biomarkers in Breath Condensate in Population of Individuals With High-Risk of Lung Cancer Undergoing LDCT Screening.

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Clinical Trial Summary
NCT ID NCT06016569
Status Recruiting
Phase
Sponsor The Institute of Molecular and Translational Medicine, Czech Republic
Condition Lung Cancer
Study Type INTERVENTIONAL
Enrollment 3,200 participants
Start Date 2023-06-01
Primary Completion 2029-12-31

Eligibility & Interventions

Sex All sexes
Min Age 55 Years
Max Age 74 Years
Study Type INTERVENTIONAL
Interventions
Exhaled breath condensate samplingBlood samplingLDCT

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 3,200 participants in total. It began in 2023-06-01 with a primary completion date of 2029-12-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The trial will evaluate if the newly identified biomarkers of lung cancer in exhaled breath condensate are as a diagnostic tool comparable to the low-dose computer tomography (LDCT) implemented in lung cancer screening recently. Due to the possibility to collect breath condensate at any medical workplace and due to the relatively low financial cost of examination of the collected breath condensate could improve early diagnosis of lung cancer, differential diagnostics of lung nodules and thereby reduce both the unnecessary interventions and deaths from this type of cancer.

Eligibility Criteria

Inclusion Criteria: 1. Consent to participate in a clinical trial. 2. A clients within an age of 55-74 years. 3. Current smoker or ex-smoker who has smoked at least 20 pack-years, provided that: 1. priority will be given to clients who have smoked at least 30 pack-years. 2. preference will be given to a former smoker who has not smoked for less than 15 years. Exclusion Criteria: 1. Previous diagnosis of lung cancer. 2. Progressing malignant tumor on symptomatic treatment. 3. Advanced dementia 4. Chronic obstructive pulmonary disease or other inflammatory disease in the phase of acute exacerbation.

Contact & Investigator

Central Contact

Marian Hajduch, MD, PhD.

✉ marian.hajduch@upol.cz

📞 +420 585632083

Principal Investigator

Marian Hajduch, MD, PhD.

STUDY DIRECTOR

IMTM, Palacky University in Olomouc, Faculty of Medicine and Dentistry

Frequently Asked Questions

Who can join the NCT06016569 clinical trial?

This trial is open to participants of all sexes, aged 55 Years or older, up to 74 Years, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06016569 currently recruiting?

Yes, NCT06016569 is actively recruiting participants. Contact the research team at marian.hajduch@upol.cz for enrollment information.

Where is the NCT06016569 trial being conducted?

This trial is being conducted at Brno, Czechia, Olomouc, Czechia, Prague, Czechia.

Who is sponsoring the NCT06016569 clinical trial?

NCT06016569 is sponsored by The Institute of Molecular and Translational Medicine, Czech Republic. The principal investigator is Marian Hajduch, MD, PhD. at IMTM, Palacky University in Olomouc, Faculty of Medicine and Dentistry. The trial plans to enroll 3,200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology