NCT05708885 Striated Esophageal Motor Function Modulation in Health and Disease
| NCT ID | NCT05708885 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Medical College of Wisconsin |
| Condition | Dysphagia, Esophageal |
| Study Type | INTERVENTIONAL |
| Enrollment | 557 participants |
| Start Date | 2022-09-13 |
| Primary Completion | 2027-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 557 participants in total. It began in 2022-09-13 with a primary completion date of 2027-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The investigators hypothesize that striated esophagus deglutitive motor function is modulated by pharyngeal phase swallowing biomechanics.
Eligibility Criteria
Inclusion Criteria: * Healthy subjects aged 18 to 90 years. * Patents with dysphagia but normal high resolution esophageal manometric findings defined by the Chicago classification. Exclusion Criteria: * Anyone less than 18 years old. * Patients with recent head and neck cancer (\<1 month post-surgery or \<3 months post-chemo radiation. * Patients suffering from muscle diseases like muscular dystrophies, myopathies. * Patients with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders. * Patients having history of allergy to lidocaine or barium. * Patients who are pregnant or lactating. * Patients who are medically unstable. * Patients who are unable to apply the exerciser independently or with the help of a caregiver. * Patients who lack cognition.
Contact & Investigator
Reza Shaker
PRINCIPAL INVESTIGATOR
Medical College of Wisconsin
Frequently Asked Questions
Who can join the NCT05708885 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 90 Years, studying Dysphagia, Esophageal. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05708885 currently recruiting?
Yes, NCT05708885 is actively recruiting participants. Contact the research team at rshaker@mcw.edu for enrollment information.
Where is the NCT05708885 trial being conducted?
This trial is being conducted at Milwaukee, United States.
Who is sponsoring the NCT05708885 clinical trial?
NCT05708885 is sponsored by Medical College of Wisconsin. The principal investigator is Reza Shaker at Medical College of Wisconsin. The trial plans to enroll 557 participants.