| NCT ID | NCT05795179 |
| Status | Recruiting |
| Phase | — |
| Sponsor | NYU Langone Health |
| Condition | Self-Control |
| Study Type | INTERVENTIONAL |
| Enrollment | 300 participants |
| Start Date | 2024-10-01 |
| Primary Completion | 2027-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 300 participants in total. It began in 2024-10-01 with a primary completion date of 2027-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Self-control failures are a universal challenge for healthy and clinical populations. Recent work suggests these failures may arise from excessive cognitive costs associated with exercising self-control, yet the mechanisms underlying these costs are unknown. To address this, the investigators will use a validated decision-making task that measures how much individuals will pay (from a study endowment) to restrict access to tempting rewards that may lead to self-control failures. The investigators will examine these costs to identify their cognitive, neural and affective mechanisms. First, the investigators will identify the cognitive and computational mechanism that gives rise to self-control costs. Second, the investigators will characterize the neural correlates of self-control costs and identify neural mediators and connectivity patterns stemming from these costs. Finally, the investigators will examine how different classes of stressors (physical, social, or lifetime stress) shape the behavioral and neural representations of self-control costs.
Eligibility Criteria
Inclusion Criteria: * 18-70 years of age, able to speak, read, and write fluently in English * be willing and able to follow study procedures and provide informed consent. * Must additionally confirm they are on a diet to maintain/lose weight and are implementing/maintaining dietary changes. Exclusion Criteria: * History of or medication for neurologic or psychiatric disease * High-blood pressure or heart condition * Diabetes, food allergies, metabolic disorders or history of eating disorder * Use of corticosteroids or beta-blockers * Metallic implants or devices contraindicating magnetic resonance imaging. * Pregnancy is considered an exclusion criteria due to all stress and scanning procedures, thus pregnant participants will not be permitted to participate in the study.
Contact & Investigator
Candace Raio
✉ candace.raio@nyulangone.orgCandace Raio
PRINCIPAL INVESTIGATOR
NYU Langone Health
Frequently Asked Questions
Who can join the NCT05795179 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 70 Years, studying Self-Control. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05795179 currently recruiting?
Yes, NCT05795179 is actively recruiting participants. Contact the research team at candace.raio@nyulangone.org for enrollment information.
Where is the NCT05795179 trial being conducted?
This trial is being conducted at New York, United States.
Who is sponsoring the NCT05795179 clinical trial?
NCT05795179 is sponsored by NYU Langone Health. The principal investigator is Candace Raio at NYU Langone Health. The trial plans to enroll 300 participants.