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Recruiting NCT04551560

Stress and Congestive Heart Failure

Trial Parameters

Condition Congestive Heart Failure
Sponsor Yale University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 112
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2020-12-02
Completion 2026-04-30
Interventions
Mental Stress

Brief Summary

The purpose of this study is to investigate whether acute stress can precipitate congestive heart failure (CHF) exacerbation in patients with CHF.

Eligibility Criteria

Inclusion Criteria: -Heart failure patients over 18 who have or will be receiving a Cardiomems implanted PAP monitor. Exclusion Criteria: * Patients who are unable to perform EMA or laboratory assessments due to cognitive, visual, language, or other disabilities will be excluded. * Patients with Class IV heart failure will also be excluded, as they are already maximally decompensated, and a ceiling/floor effect would preclude effects of stress. * Patients with conditions other than heart failure that affect PA pressures (e.g. dialysis). * Patients with physical conditions that interfere with study participation. * Patients non-compliant with their PAP monitoring. * Patients with chronic opioid use will be excluded.

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