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Recruiting NCT05426408

Stockholm Myocardial Infarction with Nonobstructive Coronaries Study 3

Trial Parameters

Condition Myocardial Infarction with Nonobstructive Coronary Arteries
Sponsor Karolinska Institutet
Study Type INTERVENTIONAL
Phase N/A
Enrollment 85
Sex ALL
Min Age 35 Years
Max Age 79 Years
Start Date 2022-11-01
Completion 2025-12-31
Interventions
Cardiac magnetic resonance imaging to study coronary microvascular dysfunction

Brief Summary

The present pilot study will investigate the prevalence of CMD in an unselected cohort of patients with the working diagnosis MINOCA and to study if the diagnostic yield can be improved by adding adenosine to the CMR investigation. Patient will be their own controls.

Eligibility Criteria

Inclusion Criteria: * a suspected diagnosis of MINOCA or takotsubo syndrome with coronary angiography without diameter stenosis ≥50% * age 35-80 years * reading and writing proficiency in Swedish Exclusion Criteria: * Claustrofobia * Arrythmia and/or pacemaker (atrial fibrillation and AV-block I- III) * Asthma or severe chronic obstructive lung disease * eGFR \< 30 ml/min * spontaneous coronary artery dissection * acute pulmonary embolism * acute myocardial infarction type 2 * cardiomyopathy other than takotsubo syndrome * a previous myocardial infarction due to CAD

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