← Back to Clinical Trials
Recruiting Phase 4 NCT07341776

Steroid Use in Treatment of Allergic Reactions to Food

Trial Parameters

Condition Anaphylactic Reaction
Sponsor Johannes Trueck
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 160
Sex ALL
Min Age 6 Months
Max Age 18 Years
Start Date 2026-01-26
Completion 2026-12
Interventions
AntihistaminesSystemic corticosteroidsAdrenaline (rescue medication)

Brief Summary

In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary. When children have allergic reactions to foods, they are often given medications to relieve the symptoms. In addition to adrenaline and antihistamines, steroids are frequently administered in German-speaking Switzerland. However, it is unclear whether steroids are really helpful in this situation. To investigate this, the investigators are comparing two groups: one group receives additional steroids, and the other does not. Which treatment a participant receives is decided randomly, like flipping a coin. The study takes place during a pre-scheduled provocation test at the clinic. If an allergic reaction occurs, the usual emergency medications will be administered. Doctors will closely monitor how the reaction develops. No additional tests or visits are required. The results of this study could help improve allergy treatment in the future.

Eligibility Criteria

Inclusion Criteria: * suspected or confirmed IgE-mediated food allergy Exclusion Criteria: * Non-IgE mediated food allergies * Non-food allergies * Age outside the specified range * Contraindications for an oral food challenge or oral steroid use within one week before the challenge.

Related Trials