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Recruiting NCT04843683

StereoTactic Ablative RadioTherapy of Cardiac Arrhythmias

Trial Parameters

Condition Cardiac Arrhythmia
Sponsor University Health Network, Toronto
Study Type INTERVENTIONAL
Phase N/A
Enrollment 60
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2021-12-14
Completion 2027-12
Interventions
Stereotactic Ablative Radiotherapy

Brief Summary

This is a prospective, single-center, phase II trial that will be monitoring the safety and efficacy of using stereotactic ablative radiotherapy (SBRT) to treat patients with a medical condition affecting heart rate and rhythm (refractory arrhythmias) within the University Health Network (Princess Margaret Cancer Centre and Toronto General Hospital). The primary objective will be to prospectively monitor patient cardiac outcomes following SBRT.

Eligibility Criteria

Inclusion Criteria: * Patients with heart rate and rhythm condition (arrhythmia) who have failed standard of care treatment with medication OR at least one prior invasive catheter ablation procedure. * Patients deemed medically fit to receive stereotactic ablative radiotherapy as determined by their Radiation Oncologist. Exclusion Criteria: * Patients who have previously received high dose radiotherapy to the target area and cannot safely receive further treatment OR are unable to receive radiotherapy due to other contraindications.

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