NCT06947538 Stepped Care for Posttraumatic Stress Disorder Study
| NCT ID | NCT06947538 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Boston Medical Center |
| Condition | Post Traumatic Stress Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 428 participants |
| Start Date | 2026-03-12 |
| Primary Completion | 2029-06 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 428 participants in total. It began in 2026-03-12 with a primary completion date of 2029-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Less than 20% of people with PTSD receive any treatment. This study extends a program of research by the investigator focused on developing adaptive (stepped) interventions for PTSD. The adaptive intervention sequences a digital mental health intervention (DMHI) and brief trauma- and skills-focused treatments for PTSD. The selected treatments are brief and scalable and less burdensome to systems of care. These treatments are: web-administered Skills Training in Affective and Interpersonal Regulation (webSTAIR), Brief STAIR, and Written Exposure Therapy (WET).
Eligibility Criteria
Inclusion criteria: Assessed at pre-screening * Boston Medical Center primary care patient * At least 18 years of age * Access to computer or mobile device * Able to receive treatments in English or Spanish * Able to read at 4th grade level Assessed at baseline * Endorsement of Criterion A trauma using the Life Events Checklist for the DSM-5 (LEC-5), assessed at baseline * PTSD diagnosis, confirmed by the Clinician-Administered PTSD Scale for the DSM-5 (CAPS-5) assessed at baseline * Clinically appropriate for outpatient level of care * Stable on psychotropic medication for \>4 weeks Exclusion criteria: Assessed at pre-screening • Patient is currently engaged in clinician-administered therapy Assessed at baseline (clinician interview) * Patient is not clinically appropriate for outpatient level of care. * Acute risk for suicidal thoughts or behaviors, assessed by the Columbia Suicide Severity Rating Scale, administered by research clinician at baseline.
Contact & Investigator
Sarah Valentine, PhD
PRINCIPAL INVESTIGATOR
Boston Medical Center, Psychiatry
Frequently Asked Questions
Who can join the NCT06947538 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Post Traumatic Stress Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06947538 currently recruiting?
Yes, NCT06947538 is actively recruiting participants. Contact the research team at sarah.valentine@bmc.org for enrollment information.
Where is the NCT06947538 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT06947538 clinical trial?
NCT06947538 is sponsored by Boston Medical Center. The principal investigator is Sarah Valentine, PhD at Boston Medical Center, Psychiatry. The trial plans to enroll 428 participants.