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Recruiting NCT03791970

Stents Post-dilation With DCB or POBA in Femoropopliteal Arteries

Trial Parameters

Condition Peripheral Artery Disease
Sponsor Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 180
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2019-01-01
Completion 2025-12-31
Interventions
Orchid 035 DCB CatheterPOBA Catheter

Brief Summary

To compare the efficacy and safety of stent angioplasty with Orchid 035 Drug Coated Dilatation (DCB) and Plain Old Balloon Angioplasty (POBA) for post-dilatation for long (\>10cm) femoropopliteal chronic total occlusion.

Eligibility Criteria

Inclusion Criteria: 1. Age ≥18 years; 2. The subject is legally competent and able to understand the information on the study, has been informed of the nature, the scope and the relevance of the study, voluntarily agrees to participation and the study's provisions, and has duly signed the Informed Consent Form (ICF); 3. Rutherford Category 2-4; 4. Target de novo lesion(s) or non-stented restenotic lesion(s) has angiographic evidence of long-term occlusion (by visual estimate ≥10cm) and is amenable to treatment with stents placement; 5. Patients must be able to be treated with DCB or POBA for post-dilation; 6. Target vessel reference diameter is 4.0-7.0 mm (by visual estimate) and able to be treated with available device size matrix; 7. At least one patent native outflow artery to the ankle free from significant lesion (≥50% stenosis) as confirmed by angiography (treatment of outflow disease is NOT permitted; treatment of in-flow disease is permitted prior to treatment with stents place

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