| NCT ID | NCT05668923 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pittsburgh |
| Condition | Stuttering, Childhood |
| Study Type | INTERVENTIONAL |
| Enrollment | 600 participants |
| Start Date | 2022-09-21 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 600 participants in total. It began in 2022-09-21 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children and whether there may be differences between children who stutter and children who do not stutter. This project will evaluate these neural processes for speech signals in children who stutter and control subjects through a battery of behavioral speech and language tests, electroencephalography-based (EEG) tasks, functional magnetic resonance imaging (fMRI), and computational modeling.
Eligibility Criteria
Inclusion Criteria: * Speaks English as primary language * Language abilities within the typical range * Cognitive abilities within the typical range * No contraindications for MRI Inclusion criteria for children who stutter: * Presence of developmental stuttering (onset in childhood) * No history of other communication disorder Inclusion criteria for children who do not stutter: * No family history of stuttering * No history of other communication disorders (e.g., hearing impairment, language impairment, cognitive impairment/injury) Exclusion Criteria: * Taking medication that alters neural function * Cognitive skills below the typical range * Major medical illness * Not a fluent speaker of English * Pregnant or possibly pregnant * Metal implants in your body (including pacemakers, neurostimulators, or other metal objects) * Shrapnel injuries * Ocular foreign bodies (e.g., metal shavings) * Metal piercings that cannot be removed for the scan * Tattoos containing iron or metal pigments * Prone to claustrophobia * For fMRI, those with head circumference greater than 60cm or whose weight is more than 300 pounds will be excluded due to the size of the fMRI magnet bore
Contact & Investigator
Amanda Hampton Wray, PhD, CCC-SLP
PRINCIPAL INVESTIGATOR
University of Pittsburgh
Frequently Asked Questions
Who can join the NCT05668923 clinical trial?
This trial is open to participants of all sexes, aged 5 Years or older, up to 17 Years, studying Stuttering, Childhood. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05668923 currently recruiting?
Yes, NCT05668923 is actively recruiting participants. Contact the research team at bmc162@pitt.edu for enrollment information.
Where is the NCT05668923 trial being conducted?
This trial is being conducted at Ann Arbor, United States, Pittsburgh, United States.
Who is sponsoring the NCT05668923 clinical trial?
NCT05668923 is sponsored by University of Pittsburgh. The principal investigator is Amanda Hampton Wray, PhD, CCC-SLP at University of Pittsburgh. The trial plans to enroll 600 participants.
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