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Recruiting NCT04997577

NCT04997577 Speech Perception and High Cognitive Demand

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Clinical Trial Summary
NCT ID NCT04997577
Status Recruiting
Phase
Sponsor University of Maryland, College Park
Condition Speech Intelligibility
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2021-09-27
Primary Completion 2026-05-30

Trial Parameters

Condition Speech Intelligibility
Sponsor University of Maryland, College Park
Study Type INTERVENTIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 65 Years
Max Age 85 Years
Start Date 2021-09-27
Completion 2026-05-30
Interventions
Auditory-cognitive training paradigmAuditory training paradigm

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Brief Summary

With advancing age, adults experience increasing speech understanding difficulties in challenging situations. Currently, speech-in-noise difficulties are rehabilitated by providing hearing aids. For older normal-hearing adults, however, hearing devices do not provide much benefit since these adults do not have decreased hearing sensitivity. The goal of the "Speech Perception and High Cognitive Demand" project is to evaluate the benefit of a new auditory-cognitive training paradigm. In the present study neural (as measured by pupillometry and magnetoencephalography) and behavioral changes of speech-in-noise perception from pretest to posttest will be examined in older adults (age 65 - 85 years) assigned to one of three training groups: 1) Active Control Group: sessions of watching informational videos, 2) Auditory Training Group: sessions of auditory training listening to one of two speakers in everyday scenarios (e.g., driving directions) and needing to recall what one speaker said in the previous sentence, and 3) Auditory-cognitive training group: identical to the auditory training group, except participants will be asked to remember information from two previous sentences. Changes in speech-in-noise perception will be examined for the three groups of older adults and gains will be compared to a control group of young, normal hearing adults (18-30 years) that is not part of the clinical trial and will not undergo any training.

Eligibility Criteria

Inclusion Criteria: * Aged between 65 - 85 years * Normal hearing (pure tone thresholds ≤ 25 dB HL from 250 - 8000 Hz) * Self-reported normal or corrected-to-normal vision * Dominant language: American English * Education: a high school diploma or higher education level Exclusion Criteria: * Middle-ear or inner-ear pathology * Non-native speaker of English * Inability to complete all training sessions within a pre-specified time window (e.g., due to unexpected schedule restrictions) * Learning disorders * Metal in body that induces a data artifact for MEG recording (e.g., excessive metal dental work) or that poses a safety issue in the MRI portion (e.g., pacemakers, neural implants, metal plates or joints, shrapnel, and surgical staples) * Claustrophobia or any condition that would be exacerbated by the scanning environment's lighting, sounds, etc. (e.g., migraines) * A non-removable hairstyle or hair accessory that would prevent the participant from fitting comfortably in the MEG or M

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