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Recruiting NCT06210451

Speculum Insertion During Embryo Transfer

Trial Parameters

Condition IVF
Sponsor Wolfson Medical Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 416
Sex FEMALE
Min Age 18 Years
Max Age 40 Years
Start Date 2024-05-01
Completion 2026-12-31
Interventions
Sterile water-based gel

Brief Summary

Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix. It was shown that applying lubricating gels significantly decreases patient pain during vaginal speculum examination. While many fertility specialists use lubrication gels to insert the speculum during embryo transfer (ET), others are strongly reluctant to use gels due to concern that they might have a detrimental effect on embryos and ET success. Similar concern was prevalent regarding the use of lubrication gel during Pap-smear for detection of cervical dysplasia. However, several studies have shown that the use of small amount of water-soluble gel does not change cervical cytology. Lubrication gels might have deleterious effect on sperm motility. However, there wasn't any study examining the effect of lubricant gel on ET success. The investigators hypothesize that using a lubrication gel will not reduce the live birth rate per transfer, but decrease patient pain during procedure.

Eligibility Criteria

Inclusion Criteria: * Age 18-40 * Fresh and thawed ET * Patients undergoing their 1st-3rd ET * ET of 1-2 embryos Exclusion Criteria: * Age\>40 * Egg donation cycles

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