NCT06968689 Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
| NCT ID | NCT06968689 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Texas Health Science Center, Houston |
| Condition | Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2025-06-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography (EEG), Functional Magnetic Resonance Imaging (fMRI), Transcranial Alternating Current Stimulation (tACS), sham and Transcranial random noise stimulation (tRNS)
Eligibility Criteria
Inclusion Criteria: * Meet the MRI / EEG screening criteria * Fluent in English Exclusion Criteria: * Current or history of major medical, neurological, or psychiatric illness based on self-report * History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment, precludes participation in the study because of a heightened potential for adverse outcome (for example: asthma or claustrophobia) * History of head trauma * Pregnant or lactating * Presence of any contraindications to MRI scanning (for example: cardiac pacemaker, metal implants, claustrophobia, pregnancy, cannot lie still in fMRI scanner) * Conditions making study participation difficult (e.g., paralysis, psychoses, or other severe psychological problems as per the judgment of a study investigator during Session 1) * Active substance abuse disorders (based on subject self-report)
Contact & Investigator
Wen Li, PhD
PRINCIPAL INVESTIGATOR
The University of Texas Health Science Center, Houston
Frequently Asked Questions
Who can join the NCT06968689 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06968689 currently recruiting?
Yes, NCT06968689 is actively recruiting participants. Contact the research team at Wen.Li.1@uth.tmc.edu for enrollment information.
Where is the NCT06968689 trial being conducted?
This trial is being conducted at Houston, United States.
Who is sponsoring the NCT06968689 clinical trial?
NCT06968689 is sponsored by The University of Texas Health Science Center, Houston. The principal investigator is Wen Li, PhD at The University of Texas Health Science Center, Houston. The trial plans to enroll 60 participants.