Sore Throat After Open Neck Elective Surgery
Trial Parameters
Brief Summary
This randomized, double-blind clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough following thyroid or parathyroid surgery with neuromonitoring. A total of 764 adult patients undergoing elective neck surgery at Saint-Petersburg State University Hospital will be enrolled and randomly assigned to receive either a hydrocortisone-coated or lidocaine-coated endotracheal tube. Outcomes will be assessed upon awakening from anesthesia, at 24 hours, and again at 3 days postoperatively. The findings may contribute to improving postoperative comfort and recovery for patients undergoing similar surgical procedures.
Eligibility Criteria
Inclusion Criteria: * Patients scheduled for elective open surgery on the thyroid/parathyroid glands with intraoperative neuromonitoring. * Age ≥18 years. * Willing and able to provide voluntary informed consent for participation in the study. Exclusion Criteria: * Pregnancy (for women of childbearing potential). * Known allergy to hydrocortisone or lidocaine. * Refusal to participate in the study.