Sonic vs Passive Ultrasonic Irrigation for Chronic Apical Periodontitis
Trial Parameters
Brief Summary
This randomized, controlled, double-blinded clinical trial aims to directly compare the efficacy of Sonically Activated Irrigation (SAI) versus Passive Ultrasonic Irrigation (PUI) in the root canal treatment of teeth with chronic apical periodontitis, analyze potential influencing factors, and thereby identify a highly effective and safe root canal irrigation protocol. The ultimate goal is to provide an evidence-based rationale for optimizing irrigation technique selection and overall treatment strategies for chronic apical periodontitis.
Eligibility Criteria
Inclusion Criteria: 1. Agree to participate in this study and provide informed consent; 2. Age 18-59 years at the time of enrolment; 3. At least one permanent tooth diagnosed with chronic periapical periodontitis at root development stage of Nolla10th; 4. Able to follow up on schedule. Exclusion Criteria: 1. Allergies to any medications or materials necessary to complete the procedures; 2. Non-restorable teeth, teeth with severe defects, or teeth that need to be extracted due to orthodontic treatment; 3. Teeth with root canal treatment or vital pulp therapy; 4. Teeth with canal calcification or root canal instrument separation; 5. Teeth with root fracture or vertical root fracture; 6. Tooth with internal or external root resorption; 7. Patients with periodontitis; 8. Patients with orthodontic treatment; 9. Presence of dental phobia; 10. Women who are pregnant; 11. Patients who have taken medications that affect central nervous system, such as tricyclic antidepressant; 12. Patients who