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Recruiting NCT05565781

NCT05565781 Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke

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Clinical Trial Summary
NCT ID NCT05565781
Status Recruiting
Phase
Sponsor Hospital Universitari Vall d'Hebron Research Institute
Condition Paroxysmal Atrial Fibrillation
Study Type INTERVENTIONAL
Enrollment 100 participants
Start Date 2022-03-28
Primary Completion 2025-06-01

Eligibility & Interventions

Sex All sexes
Min Age 55 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
ECG smartwatchInsertable Cardiac Monitor (ICM)External ECG Monitoring

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 100 participants in total. It began in 2022-03-28 with a primary completion date of 2025-06-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Stroke recurrence largely depends on the detection of the cause and the control of vascular risk factors, with occult atrial fibrillation (AF) being one of the most important. Prolonged ambulatory cardiac monitoring is recommended for detecting occult AF. Currently, there are non-invasive monitoring devices such as the textile Holter that have proven to be useful for monitoring for up to 30 days but not longer. Another alternative is smartwatches, although they must be validated for use in the elderly population who have had a stroke.

Eligibility Criteria

Inclusion Criteria: * Age greater to or equal to 55 years * Patients with diagnosis of cryptogenic stroke after a basic study that included neuroimaging, extra/intracranial vascular evaluation, 24-hour monitoring, and echocardiogram * Patients with acute cortical infarction with the presence of intracranial occlusion (preferably) * Modified Rankin Scale (mRS) lower to 4 Exclusion Criteria: * Diagnosis of lacunar infarction or transient ischemic attack (TIA) * Diagnosis of stroke of known source: atherothrombotic due to moderate or severe symptomatic extra/intracranial stenosis, major cardioembolic cause (atrial fibrillation, anterior or apical ventricular akinesis, causal PFO, post-AMI, flutter or mitral stenosis), unusual cause (thrombophilia, arterial dissection symptomatic, toxic) * Use of pacemakers * Circumstances that may preclude the clinical follow-up or reduce the possibilities of obtaining data to achieve the objectives of the study and/or limit contact with the investigator (for example, transfer to a social health center) * Unwillingness to the use of cardiac monitoring wearable devices * Not understanding study procedures

Frequently Asked Questions

Who can join the NCT05565781 clinical trial?

This trial is open to participants of all sexes, aged 55 Years or older, studying Paroxysmal Atrial Fibrillation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05565781 currently recruiting?

Yes, NCT05565781 is actively recruiting participants. Visit ClinicalTrials.gov or contact Hospital Universitari Vall d'Hebron Research Institute to inquire about joining.

Where is the NCT05565781 trial being conducted?

This trial is being conducted at Barcelona, Spain.

Who is sponsoring the NCT05565781 clinical trial?

NCT05565781 is sponsored by Hospital Universitari Vall d'Hebron Research Institute. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology