| NCT ID | NCT06824415 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Stanford University |
| Condition | Major Depression |
| Study Type | INTERVENTIONAL |
| Enrollment | 55 participants |
| Start Date | 2025-05-01 |
| Primary Completion | 2028-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 55 participants in total. It began in 2025-05-01 with a primary completion date of 2028-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.
Eligibility Criteria
Inclusion Criteria: * Adults ages 18-65 years * Current Major Depressive Disorder (MDD) diagnosis * Failed ≥1 antidepressant medication * Moderate-to-severe depression * Stable antidepressant medication dose for ≥ 6 weeks prior to enrollment * Healthy control participants are adults ages 18-65 years without current MDD symptoms, not taking antidepressant or antipsychotic medications, and without major psychiatric, neurological, substance use, medical conditions affecting brain function, or TMS/MRI contraindications. Exclusion Criteria: * Intellectual disability * Significant head injury/neurological disorder * Pregnancy or postpartum * TMS/MRI contraindications * Active substance use/suicidal ideation
Contact & Investigator
Umair Hassan, PhD
PRINCIPAL INVESTIGATOR
Stanford University
Frequently Asked Questions
Who can join the NCT06824415 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Major Depression. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06824415 currently recruiting?
Yes, NCT06824415 is actively recruiting participants. Contact the research team at kellerlab@stanford.edu for enrollment information.
Where is the NCT06824415 trial being conducted?
This trial is being conducted at Stanford, United States.
Who is sponsoring the NCT06824415 clinical trial?
NCT06824415 is sponsored by Stanford University. The principal investigator is Umair Hassan, PhD at Stanford University. The trial plans to enroll 55 participants.
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